In terms of pharmacological control of myopia, atropine has been the long dominant choice. Atropine has a long history of use in Optometry and Ophthalmology as a potent pupil dilator and accommodation suppression. It is also sometimes used in the assessment of refractive errors in pediatric eye exams. There have been numerous published studies on the use of Atropine for myopia control in children as young as six years old. These studies have shown myopia reduction ranging from 50 to as high as 80% after 2 years of use.
The concentration of Atropine needed for myopia control is much lower than that used in routine eye exams. This makes it very well tolerated by children with none of the sting of typical eye drops used for pupil dilation. It also virtually eliminates any reading blur that people will experience when having their pupils dilated during an eye exam.
Dosing for Atropine is with 1 drop to each eye at bedtime. While there is a very low incidence of pupil dilation, it has typically worn off by morning.
Aside from being the most effective way at reducing myopia progression, Atropine also allows people to continue to use their single vision glasses and contact lenses and not need to switch to a multi focusing system or incur the expense of Ortho-K.